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<p class="MsoNormal"><b><span style="font-size:12.0pt;color:black">From: </span></b><span style="font-size:12.0pt;color:black">Kristin Knouse <knouse@wi.mit.edu><br>
<b>Subject: </b>UROP Opening in Knouse Lab<o:p></o:p></span></p>
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The Knouse Lab at the Whitehead Institute is seeking undergraduate students to join our team! We harness the incredible genetic tractability and regenerative capacity of the mouse liver to investigate the reversible cell cycle state known as quiescence and
reveal novel approaches for regenerative medicine. We are currently interested in understanding the mechanisms underlying the reversibility of the quiescent state and how this state is distinct from terminal differentiation—why a hepatocyte has the ability
to divide again while a cardiomyocyte or neuron cannot. Our lab employs a variety of cell biology, genomics, and bioengineering approaches directly within the mouse. Students would initially be teamed up with other lab members to learn and assist with techniques
such as mouse colony maintenance, mouse surgeries, tissue processing, and cell isolation with the ultimate goal of having their own independent projects. For more information on our lab, please visit
<a href="http://knouselab.org">knouselab.org</a>.</span><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Students should have experience with or willingness to work with mice. Prior research experience in cell, molecular, or organismal biology is preferred but not required. Preference will be given
to students who are willing to work in the lab for multiple semesters and full-time through the summer.</span><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">If interested, please e-mail Kristin Knouse at <span class="gmail-msohyperlink"><span style="color:#0563C1"><a href="mailto:knouse@wi.mit.edu"><span style="color:#0563C1">knouse@wi.mit.edu</span></a></span></span> with
a summary of research experience and a resume or CV.</span><o:p></o:p></p>
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<span style="font-size:12.0pt;font-family:"Helvetica Neue";color:#333333">___________________________</span><span style="font-family:"Helvetica Neue";color:#333333"><o:p></o:p></span></p>
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<span style="font-size:10.5pt;font-family:"Helvetica Neue";color:#333333">Kristin Knouse, M.D., Ph.D.<br>
Fellow, Whitehead Institute for Biomedical Research<o:p></o:p></span></p>
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<span style="font-size:10.5pt;font-family:"Helvetica Neue";color:#333333">455 Main Street
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Cambridge, MA 02142<br>
Phone: 617-324-6477 (office), 617-324-2342 (lab)<br>
Email: <a href="mailto:knouse@wi.mit.edu" target="_blank"><span style="color:#444444">knouse@wi.mit.edu</span></a>
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<span style="font-size:10.5pt;font-family:"Helvetica Neue";color:#333333">Administrative Lab Manager
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Gabrielle McCauley
<br>
Phone: 617-258-5251<br>
E-mail: <a href="mailto:gabamac@wi.mit.edu" target="_blank"><span style="color:#444444">gabamac@wi.mit.edu<br>
</span></a><o:p></o:p></span></p>
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