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<p class="MsoNormal">---------- Forwarded message ---------<br>
From: <strong><span style="font-family:"Calibri",sans-serif">Ankur Jain</span></strong> <<a href="mailto:ajain@wi.mit.edu">ajain@wi.mit.edu</a>><br>
Subject: UROP<o:p></o:p></p>
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<p class="MsoNormal">My lab studies biological self-assembly. The lab uses a variety of microscopy techniques, polymer science theories and biochemical tools to understand how cells are organized, and what happens when this organization fails, such as in human
disease. I currently have two undergraduate openings in my lab: <o:p></o:p></p>
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<p class="MsoNormal">In project 1, we will study how DNA and RNA can assemble into liquids and gels in a sequence dependent manner. We will investigate how certain disease associated mutations such as the ones observed in amyotrophic lateral sclerosis lead
to misfolding and aggregation of RNA. Students will learn DNA/RNA preparatory and structure analysis methods, microscopy sample preparation, data collection and analysis. <o:p></o:p></p>
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<p class="MsoNormal">In project 2, students will study how the sequence of a RNA determines its cellular localization. The students will use molecular cloning, cell culture and live-cell fluorescence microscopy, and obtain training a variety of image analysis
methods. <o:p></o:p></p>
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