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<span style="font-size: large; font-family: Times;">PI:</span><br>
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<div class="" style="margin:0px; font-family:Times"><font size="4" class="">Jean-François Hamel, PhD</font></div>
<div class="" style="margin:0px; font-family:Times"><font size="4" class="">Office 66-371</font></div>
<div class="" style="margin:0px; font-family:Times"><font size="4" class="">E-mail:<span class="x_Apple-converted-space">&nbsp;</span><a href="mailto:jhamel@mit.edu" target="_blank" class="">jhamel@mit.edu</a></font></div>
<div class="" style="margin:0px; font-family:Times"><font size="4" class="">Phone: (617) 258-6665</font></div>
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<font face="Times New Roman" size="3" class="">Proposed Summer Energy UROP Project<span class="x_Apple-converted-space">&nbsp;</span></font><span class="" style="background-color:rgb(255,255,0)"><font face="Times New Roman" size="3" class="">(deadline for direct
 MITEI funding is April 8th)</font></span></font><font face="Times New Roman" size="3" class=""><span class="" style="font-size:12pt"></span>
<div class="" style="margin-top:0px; margin-bottom:0px"><span class="" style="font-size:12pt; line-height:18.399999618530273px">Biological approaches for improving CO<sub class="">2</sub><span class="x_Apple-converted-space">&nbsp;</span>capture, and production
 of algal fatty acids for biodiesel production</span></div>
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<div class="" style="margin-top:0px; margin-bottom:0px">Overall Objective:</div>
The project focuses on the study of</font><font face="Times New Roman" size="3" class=""><span class="" style="font-size:12pt"><span class="x_Apple-converted-space">&nbsp;</span>the effect of nutrients and algae culture conditions (e.g., illumination profile) on
 CO<sub class="">2</sub><span class="x_Apple-converted-space">&nbsp;</span>capture and fatty acids production, and to examine biological routes (e.g., enzymatic) for improving fatty acids recovery and purification.</span>
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Proposed Summer<span class="x_Apple-converted-space">&nbsp;</span></font><font face="Times New Roman" size="3" class=""><font face="Times New Roman" size="3" class="">Biotech<span class="x_Apple-converted-space">&nbsp;</span></font>UROP Project<span class="x_Apple-converted-space">&nbsp;</span><span class="" style="background-color:rgb(0,255,255)">(deadline
 for direct UROP funding is April 14th)</span><br class="">
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<div class="" style="margin:0px"><font size="3" class="">Production of isotopically-enriched serum albumin for biomedical research using<span class="x_Apple-converted-space">&nbsp;</span><i class="">Pichia</i></font></div>
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<div class="" style="margin:0px"><font size="3" class=""><i class="">pastoris</i><span class="x_Apple-converted-space">&nbsp;</span>as a biosynthetic host</font></div>
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<div class="" style="margin:0px"><font size="3" class="">Overall Objective:</font></div>
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<div class="" style="margin:0px"><font size="3" class="">The project focuses on the development and optimization of the substrate yield of a novel process</font></div>
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<div class="" style="margin:0px"><font size="3" class="">that uses [13C6]glucose and [15N2]ammonium sulfate to produce isotopically-labeled serum</font></div>
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<div class="" style="margin:0px"><font size="3" class="">albumin from the yeast<span class="x_Apple-converted-space">&nbsp;</span><i class="">Pichia pastoris</i>, with robust and consistent quantity and enrichment for</font></div>
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<div class="" style="margin:0px"><font size="3" class="">biomedical research applications.</font></div>
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