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<div><font size="4">Dear Students,</font></div>
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<div><font size="4">This a reminder that that there are three new restricted biology electives for 2015-2016. <b>Hallmarks of Cancer (7.45)</b> and
<b>Engineering Principles underlying Novel Biotherapeutics (7.371)</b> will be held in the
<b>Fall 2015 semester</b>. </font></div>
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<div><font size="4"><b>Quantitative and Computational Biology (7.09) </b>will be offered in
<b>Spring 2016</b>.</font></div>
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<div><font size="4">Other Fall 2015 electives include: 7.20 Human Physiology, 7.21 Microbial Physology, 7.22 Development and Evolution, 7.23 Immunology, 7.30AB Fundamentals of Ecology I&II, 7.31 Current Topics in Mammalian Biology, and 7.32 Systems Biology.</font></div>
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<div><font size="4">Please initiate your preregistration by <b>Monday, June 15th</b>; a late of $50 will be assessed if pre-registration is not completed by this date. Course selections can be modified through Thursday, August 18th. </font></div>
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<b>FALL 2015</b></div>
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7.371 Biological and Engineering Principles Underlying Novel Biotherapeutics <br>
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<img apple-inline="yes" id="75515480-BECB-41EE-9B5C-048AEE225D29" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:97FFC9C2-83C7-459A-B0A4-D067D124F860@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><img apple-inline="yes" id="14F22761-64CF-4660-89D2-08A1DA0021BA" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:9E7FE572-ABC0-4251-9FF5-5784600C5E24@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Prereq: </span><a href="http://student.mit.edu/catalog/m7a.html#7.06" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.06</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Units: 4-0-8 </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Credit cannot also be received for </span><a href="http://student.mit.edu/catalog/m7a.html#7.37" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.37</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">, </span><a href="http://student.mit.edu/catalog/m10a.html#10.441" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">10.441</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">, </span><a href="http://student.mit.edu/catalog/m20a.html#20.361" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">20.361</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<a href="http://student.mit.edu/catalog/editcookie.cgi?add=7.371" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"><img apple-inline="yes" id="27A01F13-BFE4-4B8E-BB00-14F06D4C47DC" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:1D53743B-DE07-4EE7-94CF-F40278FD0D03@mit.edu"></a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><b style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Lecture:</b><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">MW3-5</i><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><a href="http://whereis.mit.edu/map-jpg?mapterms=WI%207TH" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">WI
7TH</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">)</span><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<img apple-inline="yes" id="7D965CA9-12A2-4006-A174-E9E413DEB3F0" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:B2F6A1FD-F407-493A-8B94-72ECD83509EA@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Covers biological and bioengineering principles underlying the development and therapeutic use
of recombinant proteins and immune cells. Special attention to monoclonal antibodies and engineered immune system cells as therapeutics; protein- and glyco- engineering to enhance protein function; protein pharmacology and delivery; nucleic acid- based biotherapeutics;
generation of functional cells and tissues from embryonic stem cells and iPS cells; and macrophages in health and diseases. </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">J. Chen, H. Lodish</i></div>
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7.45 The Hallmarks of Cancer <br>
(New) <br>
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<img apple-inline="yes" id="54C65469-3A9E-4F3B-87B1-DB985D6A829A" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:582F0B2D-96E3-4593-B42F-B34BE54EF439@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><img apple-inline="yes" id="4DF2001E-9EBC-4A17-94B4-2529C74132FD" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:E89F4A51-48D6-49F2-ACB1-561D8A1B6FB2@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">(Subject meets with </span><a href="http://student.mit.edu/catalog/m7a.html#7.85" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.85</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Prereq: </span><a href="http://student.mit.edu/catalog/m7a.html#7.06" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.06</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Units: 4-0-8 </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<a href="http://student.mit.edu/catalog/editcookie.cgi?add=7.45" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"><img apple-inline="yes" id="5432C2B3-84E1-4D2D-B613-1C7BD4D54844" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:D5D1C35C-56D3-4EFF-B45F-869A613FD1BC@mit.edu"></a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><b style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Lecture:</b><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">TR11-12.30</i><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><a href="http://whereis.mit.edu/map-jpg?mapterms=E25" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">E25-111</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">)</span><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<img apple-inline="yes" id="1820D6D0-A30C-4761-B346-BADA97AF1D8D" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:47023D43-4E0F-4A10-A53B-C4E856E9B9E9@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Provides a comprehensive introduction to the fundamentals of cancer biology and cancer treatment.
Topics include cancer genetics, genomics, and epigenetics; familial cancer syndromes; signal transduction, cell cycle control, and apoptosis; cancer metabolism; stem cells and cancer; metastasis; cancer immunology and immunotherapy; conventional and molecularly-targeted
therapies; and early detection and prevention. Students taking graduate version complete additional assignments. </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">T. Jacks, M. Vander Heiden</i></div>
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<div><b>SPRING 2016</b></div>
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7.09 Quantitative and Computational Biology <br>
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<img apple-inline="yes" id="D46F0C8E-C342-4572-B01B-E719EF59F66E" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:4A203B51-0FA3-43F4-8064-D517AFA0E82A@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><img apple-inline="yes" id="B9A8AD75-9F46-468F-8EC3-8BAA100948AD" height="16" width="16" apple-width="yes" apple-height="yes" src="cid:1728640A-454D-466C-856A-CA740A5B2D4A@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Prereq: </span><a href="http://student.mit.edu/catalog/m7a.html#7.03" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.03</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">, </span><a href="http://student.mit.edu/catalog/m7a.html#7.05" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.05</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Units: 3-0-9 </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<img apple-inline="yes" id="C03866A5-B504-4589-80AF-CB9A7FD53881" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:7EA97563-97DB-4351-874B-47D5960775F6@mit.edu"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Quantitative and computational analysis of biological systems at the molecular and cellular level.
Includes models of biological processes across different time scales, from steady-state to kinetics of gene expression, circadian clock, cell growth, and evolutionary dynamics. Methods include physical, systems, and synthetic biology. Also covers second-generation
sequencing technologies, and topics in computational analysis of genomes, including sequence alignment, motif finding, information theory and RNA secondary structure prediction. </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">C. Burge, G. W. Li</i></div>
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