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<span style="font-size: large; ">Dear Biology Majors,</span></div>
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<div><span style="font-size: large; ">Regarding the new restricted electives for 2015-2016, I'd like to point out that both </span><span style="font-size: large; "><b>Engineering Principles Underlying Novel Biotherapeutics (7.371)</b>and </span><b style="font-size: large; ">The
Hallmarks of Cancer (7.45)</b><span style="font-size: large; "> will be held in the <u>Fall 2015</u> semester, while </span><font size="4">Quantitative and Computation Biology (7.09) will held in Spring 2016. Previously, 7.371 was mentioned as being held in
the Spring, which is not the case. Apologies for any confusion or inconvenience. </font></div>
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<div><font size="4">Again, please remember to pre-register by June 15th.</font></div>
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<div><font size="4">Best wishes for a great summer,</font></div>
<div><font size="4">Joyce</font></div>
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<div><b>FALL 2015</b></div>
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7.371 Biological and Engineering Principles Underlying Novel Biotherapeutics <br>
(New) <br>
<img alt="______" apple-inline="yes" id="1EEDC88E-462F-406F-88DA-0A18A09A3510" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:8E5F2630-2990-456A-B29E-61489C772F22@cable.rcn.com"></h3>
<img width="16" height="16" align="bottom" alt="Undergrad" title="Undergrad" apple-inline="yes" id="EEAB5DD3-420B-4910-9B70-8A443A4E753D" apple-width="yes" apple-height="yes" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); " src="cid:C67ACFEA-8154-40C3-96F6-05DD415A7351@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> (</span><img width="16" height="16" align="bottom" alt="Fall" title="Fall" apple-inline="yes" id="2CE24B64-B9CE-41FD-B9FA-6C370B5F9C0C" apple-width="yes" apple-height="yes" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); " src="cid:23BD9EBC-D0EF-4E4E-8862-E67AB13283AB@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">Prereq: </span><a href="http://student.mit.edu/catalog/m7a.html#7.06" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">7.06</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">Units: 4-0-8 </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">Credit cannot also be received for </span><a href="http://student.mit.edu/catalog/m7a.html#7.37" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">7.37</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">, </span><a href="http://student.mit.edu/catalog/m10a.html#10.441" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">10.441</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">, </span><a href="http://student.mit.edu/catalog/m20a.html#20.361" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">20.361</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<a href="http://student.mit.edu/catalog/editcookie.cgi?add=7.371" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "><img align="bottom" border="1" width="16" height="16" alt="Add to schedule" title="Add to schedule" apple-inline="yes" id="0C07DA9D-4E08-425D-8D17-A38ED146F167" apple-width="yes" apple-height="yes" src="cid:5BE3ABEC-99CC-415A-A816-9242DD751A33@cable.rcn.com"></a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> </span><b style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">Lecture:</b><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> </span><i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">MW3-5</i><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> (</span><a href="http://whereis.mit.edu/map-jpg?mapterms=WI%207TH" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">WI
7TH</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">)</span><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<img alt="______" apple-inline="yes" id="61F38CB4-0A56-410B-8AC4-AD4415AE6B19" height="9" width="302" apple-width="yes" apple-height="yes" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); " src="cid:8E5F2630-2990-456A-B29E-61489C772F22@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); "> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">Covers biological and bioengineering principles underlying the development and therapeutic use
of recombinant proteins and immune cells. Special attention to monoclonal antibodies and engineered immune system cells as therapeutics; protein- and glyco- engineering to enhance protein function; protein pharmacology and delivery; nucleic acid- based biotherapeutics;
generation of functional cells and tissues from embryonic stem cells and iPS cells; and macrophages in health and diseases. </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">
<i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255); ">J. Chen, H. Lodish</i></div>
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7.45 The Hallmarks of Cancer <br>
(New) <br>
<img alt="______" apple-inline="yes" id="E398E193-C56F-40D5-BEEB-05B010DF5AA7" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:EC79B452-DB8E-47FE-9066-8DD3AB625D7C@cable.rcn.com"></h3>
<img width="16" height="16" align="bottom" alt="Undergrad" title="Undergrad" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);" apple-inline="yes" id="9F9493DC-A118-4E83-805A-3673514701F0" apple-width="yes" apple-height="yes" src="cid:336B7050-0C72-41AD-B394-BAAD7619C6A0@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><img width="16" height="16" align="bottom" alt="Fall" title="Fall" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);" apple-inline="yes" id="583B901B-7B02-4E72-A90F-FE0103004A8C" apple-width="yes" apple-height="yes" src="cid:89A422EC-D550-44BF-90E0-2043C0BBDDCB@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">(Subject meets with </span><a href="http://student.mit.edu/catalog/m7a.html#7.85" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.85</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Prereq: </span><a href="http://student.mit.edu/catalog/m7a.html#7.06" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.06</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Units: 4-0-8 </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<a href="http://student.mit.edu/catalog/editcookie.cgi?add=7.45" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"><img align="bottom" border="1" width="16" height="16" alt="Add to schedule" title="Add to schedule" apple-inline="yes" id="0CB21572-16A2-412A-AC33-942EA6556797" apple-width="yes" apple-height="yes" src="cid:A0523976-5D8D-4BF2-934C-346157A69F6F@cable.rcn.com"></a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><b style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Lecture:</b><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">TR11-12.30</i><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><a href="http://whereis.mit.edu/map-jpg?mapterms=E25" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">E25-111</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">)</span><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<img alt="______" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);" apple-inline="yes" id="14ECAC10-29F6-4DC4-82B4-181D2F0F505F" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:EC79B452-DB8E-47FE-9066-8DD3AB625D7C@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Provides a comprehensive introduction to the fundamentals of cancer biology and cancer treatment.
Topics include cancer genetics, genomics, and epigenetics; familial cancer syndromes; signal transduction, cell cycle control, and apoptosis; cancer metabolism; stem cells and cancer; metastasis; cancer immunology and immunotherapy; conventional and molecularly-targeted
therapies; and early detection and prevention. Students taking graduate version complete additional assignments. </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">T. Jacks, M. Vander Heiden</i></div>
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<div><b>SPRING 2016</b></div>
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7.09 Quantitative and Computational Biology <br>
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<img width="16" height="16" align="bottom" alt="Undergrad" title="Undergrad" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);" apple-inline="yes" id="2F399A6B-CA21-4938-8101-56467846C3B9" apple-width="yes" apple-height="yes" src="cid:12974D02-88C7-436A-85DC-B15D77ED8C33@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> (</span><img width="16" height="16" align="bottom" alt="Spring" title="Spring" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);" apple-inline="yes" id="FB6107C7-6F79-4BF0-AFAF-0A77FDF1499C" apple-width="yes" apple-height="yes" src="cid:C0514BB9-3387-486D-B8A7-7AA0C4F8002E@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">) </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Prereq: </span><a href="http://student.mit.edu/catalog/m7a.html#7.03" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.03</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">, </span><a href="http://student.mit.edu/catalog/m7a.html#7.05" style="text-decoration: none; color: rgb(0, 102, 153); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">7.05</a><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Units: 3-0-9 </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<img alt="______" style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);" apple-inline="yes" id="49E7F216-9CC4-42B1-BB91-CBCDD8216480" height="9" width="302" apple-width="yes" apple-height="yes" src="cid:2DAA39D5-536B-44BB-8D69-C69C0654C164@cable.rcn.com"><span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);"> </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<span style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">Quantitative and computational analysis of biological systems at the molecular and cellular level.
Includes models of biological processes across different time scales, from steady-state to kinetics of gene expression, circadian clock, cell growth, and evolutionary dynamics. Methods include physical, systems, and synthetic biology. Also covers second-generation
sequencing technologies, and topics in computational analysis of genomes, including sequence alignment, motif finding, information theory and RNA secondary structure prediction. </span><br style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">
<i style="color: rgb(51, 51, 51); font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 15px; background-color: rgb(255, 255, 255);">C. Burge, G. W. Li</i></div>
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<div><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px; ">
<div>Joyce Roberge<br>
Undergraduate Program<br>
Biology Education Office 68-120<br>
Massachusetts Institute of Technology<br>
31 Ames Street<br>
Cambridge, MA 02139<br>
617-253-4718<br>
fax: 617-258-9329<br>
email: <a href="mailto:roberge@mit.edu">roberge@mit.edu</a></div>
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