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<div style="margin:0px; font-family:Times"><font size="4"> PI:</font></div>
<div style="margin:0px; font-family:Times"><font size="4">Jean-François Hamel, PhD</font></div>
<div style="margin:0px; font-family:Times"><font size="4">Office 66-371</font></div>
<div style="margin:0px; font-family:Times"><font size="4">E-mail: <a href="mailto:jhamel@mit.edu">
jhamel@mit.edu</a></font></div>
<div style="margin:0px; font-family:Times"><font size="4">Phone: (617) 258-6665</font></div>
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<div style="margin:0px; font-family:Times"><font size="4">Proposed Summer UROP Project</font></div>
<div style="margin:0px; font-family:Times"><font size="4">Production of isotopically-enriched serum albumin for biomedical research using Pichia</font></div>
<div style="margin:0px; font-family:Times"><font size="4">pastoris as a biosynthetic host</font></div>
<div style="margin:0px; font-family:Times"><font size="4"><br>
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<div style="margin:0px; font-family:Times"><font size="4">Overall Objective:</font></div>
<div style="margin:0px; font-family:Times"><font size="4">The project focuses on the development and optimization of the substrate yield of a novel process</font></div>
<div style="margin:0px; font-family:Times"><font size="4">that uses [13C6]glucose and [15N2]ammonium sulfate to produce isotopically-labeled serum</font></div>
<div style="margin:0px; font-family:Times"><font size="4">albumin from the yeast Pichia pastoris, with robust and consistent quantity and enrichment for</font></div>
<div style="margin:0px; font-family:Times"><font size="4">biomedical research applications.</font></div>
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