<HTML><BODY style="word-wrap: break-word; -khtml-nbsp-mode: space; -khtml-line-break: after-white-space; "><DIV>Thanks for the input; below are the details related to the UROP position:</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV class="MsoNormal"> <O:P></O:P></DIV><DIV class="MsoNormal">UROP position<O:P></O:P></DIV><DIV class="MsoNormal">IAP and Spring 2007<O:P></O:P></DIV><DIV class="MsoNormal">Biology and Whitehead Institute<O:P></O:P></DIV><DIV class="MsoNormal">Faculty Supervisor: Peter Reddien<O:P></O:P></DIV><DIV class="MsoNormal"> <O:P></O:P></DIV><DIV class="MsoNormal">There is an opening for a UROP in the Reddien lab at the Whitehead Institute in the Biology Department. The ability to regenerate missing body parts is one of the great mysteries of biology. The Reddien lab studies regeneration in planarians: an emerging molecular genetic system in which RNA interference can be utilized and many molecular resources are available. Regeneration is accomplished via the action of a population of stem cells called neoblasts. This project relates to the characterization of monoclonal antibodies that recognize planarian proteins. Specifically, hybridomas created from mice immunized with planarian cells or proteins exist and will be screened for production of antibodies recognizing planarian proteins and cells using a microarray-based, high-throughput approach.<SPAN style="mso-spacerun: yes"> </SPAN>Fluorescent antibody labelings will be utilized to screen for labeling patterns in animals or on isolated cells. Goals include development of markers for the planarian stem cells and markers for other tissues and cell types for phenotypic analyses. The UROP position would start in IAP or at the beginning of the spring semester and continue through the semester. <O:P></O:P></DIV><DIV class="MsoNormal"> <O:P></O:P></DIV><DIV class="MsoNormal">Prerequisites:<SPAN style="mso-spacerun: yes"> </SPAN>7.02 or equivalent, familiarity with basic cell and molecular biology.<O:P></O:P></DIV><DIV class="MsoNormal"> <O:P></O:P></DIV><DIV class="MsoNormal">Contact: <A href="mailto:reddien@wi.mit.edu">reddien@wi.mit.edu</A><O:P></O:P></DIV><SPAN style=""><FONT class="Apple-style-span" face="Times" size="4"><SPAN class="Apple-style-span" style="font-size: 16px;"><A href="http://inside.wi.mit.edu/reddien/pub/PWR_website/Rddn_home.html">http://inside.wi.mit.edu/reddien/pub/PWR_website/Rddn_home.html</A></SPAN></FONT></SPAN> <DIV><BR class="khtml-block-placeholder"></DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV><BR class="khtml-block-placeholder"></DIV><BR><DIV><DIV>On Dec 6, 2006, at 11:20 AM, MacKenzie Outlund wrote:</DIV><BR class="Apple-interchange-newline"><BLOCKQUOTE type="cite"><DIV>Hello Dr. Reddien,</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>In fact, it may be simpler for everyone if you would just send us any announcements you'd like the biology undergraduates to receive. Janice or I generally post most of the messages to the list, so you may send the posts to jdchang@mit or <A href="mailto:moutlund@mit.edu">moutlund@mit.edu</A>.</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>Thanks!</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>Best, </DIV><BR><DIV> <SPAN class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px 0px; color: rgb(0, 0, 0); font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: auto; -khtml-text-decorations-in-effect: none; text-indent: 0px; -apple-text-size-adjust: auto; text-transform: none; orphans: 2; white-space: normal; widows: 2; word-spacing: 0px; "><SPAN class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px 0px; color: rgb(0, 0, 0); font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: auto; -khtml-text-decorations-in-effect: none; text-indent: 0px; -apple-text-size-adjust: auto; text-transform: none; orphans: 2; white-space: normal; widows: 2; word-spacing: 0px; "><SPAN class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px 0px; color: rgb(0, 0, 0); font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: auto; -khtml-text-decorations-in-effect: none; text-indent: 0px; -apple-text-size-adjust: auto; text-transform: none; orphans: 2; white-space: normal; widows: 2; word-spacing: 0px; "><SPAN class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px 0px; color: rgb(0, 0, 0); font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: auto; -khtml-text-decorations-in-effect: none; text-indent: 0px; -apple-text-size-adjust: auto; text-transform: none; orphans: 2; white-space: normal; widows: 2; word-spacing: 0px; "><SPAN class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px 0px; color: rgb(0, 0, 0); font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: auto; -khtml-text-decorations-in-effect: none; text-indent: 0px; -apple-text-size-adjust: auto; text-transform: none; orphans: 2; white-space: normal; widows: 2; word-spacing: 0px; ">MacKenzie Outlund<BR class="Apple-interchange-newline"></SPAN><DIV>Undergraduate Program</DIV><DIV>Biology Education Office 68-120</DIV><DIV>Massachusetts Institute of Technology</DIV><DIV>77 Massachusetts Avenue</DIV><DIV>Cambridge, MA 02139</DIV><DIV>(617)253-4718</DIV><DIV>fax: (617) 258-9329</DIV><A href="http://mit.edu/biology/www/undergrad/">http://mit.edu/biology/www/undergrad/</A><BR class="Apple-interchange-newline"></SPAN></SPAN></SPAN></SPAN> </DIV><BR></BLOCKQUOTE></DIV><BR></BODY></HTML>