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<div align="center"><font size="+2" color="#FF0000"><b>Biochemistry
Seminar</b></font></div>
<div align="center"><font size="+1" color="#000000">Thursday, January
26, 2006</font></div>
<div align="center"><font size="+1" color="#000000">Dr. C. Robert
Matthews</font></div>
<div align="center"><font size="+1" color="#000000">University of
Massachusetts Medical School</font></div>
<div align="center"><font size="+1" color="#000000">"Sequence vs.
Topology in the Control of TIM Barrel Folding
Reactions"</font></div>
<div align="center"><font size="+1"
color="#000000">68-181</font></div>
<div align="center"><font size="+1" color="#000000">NOON</font></div>
<div align="center"><font size="+1" color="#000000">Hosted by Dr.
Jonathan King</font></div>
<div><font size="+1" color="#000000"><br></font></div>
<div><font size="+1" color="#000000">Dr. Matthews graduated from the
University of Minnesota and received his PhD from Stanford University.
He is currently the principal investigator for a range of research
projects funded through the National Institutes of Health and National
Science Foundation in the areas of enzyme structure and function and
peptide and protein folding. His investigations are particularly
focused on how single amino acids affect protein conformation - an
area of great potential for drug discovery and drug design. Dr.
Matthews is the author of nearly 100 scientific publications. He also
serves on the editorial boards of the Journal of Protein Engineering
and the Biophysical Journal, is the associate editor of the Journal of
Molecular Biology and, in 1995, served as the co-chair of the Protein
Society's Ninth International Symposium held in Boston.</font><font
size="+1"> Dr. Matthews is currently Professor and Chair of
Biochemistry & Molecular Pharmacology at the University of
Massachusetts Medical School.</font></div>
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